POGZ Antikörper

Produktnummer ABIN7861934

Dieser Maus Monoklonal Antikörper detektiert spezifisch POGZ in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für POGZ Antikörper (ABIN7861934)

Target: POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser POGZ Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: PCRP-POGZ-1B2

Produktdetails anti-POGZ Antikörper

Verwendungszweck: POGZ Antibody

Spezifität: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human POGZ protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu POGZ

Target: POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

Andere Bezeichnung: POGZ

Hintergrund:

KIAA0461, ZNF280E, ZNF635m, Pogo transposable element with ZNF domain

HeLa or U87 cells. Human placenta|tonsil or colon.

Molekulargewicht: 155.3kDa

Gen-ID: 23126, 25040

UniProt: Q7Z3K3