Rekombinanter CD70 Antikörper (C-Term)

Produktnummer ABIN7860692

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CD70 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CD70 Antikörper (C-Term) (ABIN7860692)

Target: CD70 (CD70 Molecule (CD70))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: CD70-12768R

Produktdetails anti-CD70 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Recombinant CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody

Spezifität: It recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment corresponding to the C-terminus of human CD70 protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund:

CD27 ligand (CD27L), CD27LG, Ki24, Surface antigen CD70, Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7)

Raji cells. Lymph node or tonsil.

Molekulargewicht: 30kDa

Gen-ID: 970, 501497, 715224

UniProt: P32970

Pathways: Cancer Immune Checkpoints