Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid. Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiation of benign and malignant thyroid neoplasms. Galectin-3 may also be useful in the identification of certain liver disorders.
Aufreinigung
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
Immunogen
Recombinant fragment (around aa1-250) of human LGALS3 protein (exact sequence is proprietary)
LGALS3
Reaktivität: Human
WB, IHC, ELISA, IF, IP
Wirt: Kaninchen
Monoclonal
4E1
unconjugated
Recombinant Antibody
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
200 μg/mL
Buffer
Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Target
Galectin 3 (LGALS3)
Andere Bezeichnung
Galectin-3
Hintergrund
Human papillary thyroid carcinoma tissue. MCF-7 cells.