Hexokinase 1 Antikörper (AA 1-200)
Kurzübersicht für Hexokinase 1 Antikörper (AA 1-200) (ABIN7865266)
Target
Alle Hexokinase 1 (HK1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-200
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Verwendungszweck
- HK1 / Hexokinase 1 Antibody
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Spezifität
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa1-200) of human HK1 protein (exact sequence is proprietary)
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Hexokinase 1 (HK1)
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Andere Bezeichnung
- HK1
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Hintergrund
- Neuropathy, hereditary motor and sensory, Russe type
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Molekulargewicht
- 102kDa
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Gen-ID
- 3098, 370365
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UniProt
- P19367
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Pathways
- Carbohydrate Homeostasis, Warburg Effekt
Target
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