Rekombinanter PD-1 Antikörper (Extracellular Domain)

Produktnummer ABIN7858035

Der Kaninchen Monoklonal anti-PD-1 Antikörper wird verwendet zum Nachweis von PD-1 in Proben von Human. Er wurde validiert für IHC und ELISA.

Kurzübersicht für Rekombinanter PD-1 Antikörper (Extracellular Domain) (ABIN7858035)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PD-1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Klon: PDCD1-7276R

Produktdetails anti-PD-1 Antikörper

Bindungsspezifität: Extracellular Domain

Verwendungszweck: Recombinant PDCD1 / PD1 / CD279 (Programmed Cell Death 1) Antibody

Spezifität: PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

Aufreinigung: 200ug/ml of Ab purified by Protein A/G.

Immunogen: Recombinant fragment corresponding to extracellular domain of human PDCD1 protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: PDCD1

Hintergrund:

CD279, hPD-1, hSLE1, PD1, PDCD1, Programmed Cell Death Protein 1, Protein PD-1, SLEB2, Systemic lupus erythematosus susceptibility 2

Human tonsil|lymph node or appendix.

Molekulargewicht: 55kDa

Gen-ID: 5133, 158297

UniProt: Q15116

Pathways: Cancer Immune Checkpoints