Tyrosinase-Related Protein 1 Antikörper (AA 200-400)
Kurzübersicht für Tyrosinase-Related Protein 1 Antikörper (AA 200-400) (ABIN7857990)
Target
Alle Tyrosinase-Related Protein 1 (TYRP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 200-400
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Verwendungszweck
- Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Antibody
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Spezifität
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. 79oΩRecent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
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Aufreinigung
- 200ug/ml of Ab purified by Protein A.
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Immunogen
- Recombinant fragment (around aa200-400) of human TYRP1 protein (exact sequence is proprietary)
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Isotyp
- IgG, kappa
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anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibody
TYRP1 Reaktivität: Human, Maus, Ratte, Hund, Ziege, Pferd, Kaninchen, Schaf, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio) IHC, WB Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 Reaktivität: Human IHC, WB, ELISA Wirt: Kaninchen Monoclonal TYRP1-2340R unconjugated Recombinant Antibody
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 198-227) antibodyTYRP1 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB19412 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal TYRP1-3280 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 396-445) antibodyTYRP1 Reaktivität: Human, Maus, Ratte, Hund, Ziege, Pferd, Kaninchen, Schaf, Meerschweinchen, Zebrafisch (Danio rerio), Huhn, Affe, Fledermaus IHC, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 Reaktivität: Human, Maus IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 Reaktivität: Human, Maus IHC Wirt: Kaninchen Monoclonal TYRP1-1564R unconjugated Recombinant Antibody
anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibodyTYRP1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Tyrosinase-Related Protein 1 (TYRP1)
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Andere Bezeichnung
- Tyrosinase-Related Protein-1
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Hintergrund
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5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP
SK-MEL-19|SK-MEL-23|SK-MEL-30 or SK-MEL-37 cells. Human melanoma.
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Molekulargewicht
- 75kDa
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Gen-ID
- 7306, 270279
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UniProt
- P17643
Target
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