Rekombinanter Prostate Specific Antigen Antikörper
Kurzübersicht für Rekombinanter Prostate Specific Antigen Antikörper (ABIN7862988)
Target
Alle Prostate Specific Antigen (PSA) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Expressionssystem
- CHO Cells
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Verwendungszweck
- Recombinant Prostate Specific Antigen (PSA) Antibody
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Spezifität
- Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb 1A7G6B6 for PSA tests.
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Aufreinigung
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogen
- Recombinant full-length human KLK3 (PSA) protein
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- Prostate Specific Antigen (PSA)
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Andere Bezeichnung
- Prostate Specific Antigen
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Hintergrund
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Antigen, prostate-specific (APS), Gamma-seminoprotein, hK3, Kallikrein related peptidase 3, Kallikrein-3 (KLK3), KLK2A1, P-30 antigen, Semenogelase, Seminin
PC12 cells. Normal prostate or prostate carcinoma tissues.
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Molekulargewicht
- 33-34kDa
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Gen-ID
- 354, 171995
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UniProt
- P07288
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Pathways
- Komplementsystem
Target
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