PSME4 Antikörper (AA 840-1140)

Produktnummer ABIN7833480

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PSME4 in WB. Es zeigt Reaktivität gegenüber Proben von Arabidopsis thaliana.

Kurzübersicht für PSME4 Antikörper (AA 840-1140) (ABIN7833480)

Target: PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))

Reaktivität: Arabidopsis thaliana

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSME4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PSME4 Antikörper

Bindungsspezifität: AA 840-1140

Verwendungszweck: Anti-PA200 | Proteasome activator PA200

Kreuzreaktivität (Details): Arabidopsis thaliana
Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Aufreinigung: Serum

Immunogen: PA200 antibodies were generated against a partial fragment encompassing residues 840-1140 Arabidopsis thaliana protein sequence UniProt:F4JC97-1

Anwendungsinformationen

Applikationshinweise: 1 : 500 (WB)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 50 μL, of sterile water

Buffer: Serum

Handhabung: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store lyophilized/reconstituted at -20°C (short tem, months) or at -80°C (long term, years) , once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Details zu PSME4

Target: PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))

Andere Bezeichnung: PA200

Hintergrund: PA200 (Proteasome activator PA200) is an associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. It also recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA damage response: binds to acetylated histones and promotes degradation of histones. Protein levels increase upon exposure of seedlings to MG132, a specific, potent, reversible, and cell-permeable proteasome inhibitor. Alternative names: Proteasome activator subunit 4, Proteasome activating protein 200.

Molekulargewicht: 202.9 | ca. 200 kDa

Gen-ID: 820533

UniProt: F4JC97-1

Pathways: DNA Replication, Synthesis of DNA