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PSME4 Antikörper (AA 503-535)

PSME4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB55279 unconjugated
Produktnummer ABIN6242866
  • Target Alle PSME4 Antikörper anzeigen
    PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))
    Bindungsspezifität
    • 4
    • 1
    • 1
    AA 503-535
    Reaktivität
    • 7
    • 2
    • 2
    Human
    Wirt
    • 7
    Kaninchen
    Klonalität
    • 7
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    Dieser PSME4 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PSME4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 503-535 amino acids from human PSME4.
    Klon
    RB55279
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PSME4 Primärantikörper
  • Applikationshinweise
    WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))
    Andere Bezeichnung
    PSME4 (PSME4 Produkte)
    Synonyme
    proteasome activating protein 200 antikoerper, Afu4g11290 antikoerper, An04g05320 antikoerper, AO090003001091 antikoerper, PA200 antikoerper, AA409398 antikoerper, AU041366 antikoerper, TEMO antikoerper, mKIAA0077 antikoerper, proteasome activator subunit 4 antikoerper, proteasome activating protein 200 antikoerper, proteasome (prosome, macropain) activator subunit 4 antikoerper, PSME4 antikoerper, Psme4 antikoerper, PA200 antikoerper, AFUA_4G11290 antikoerper, ANI_1_888184 antikoerper, AOR_1_1944154 antikoerper, TERG_07227 antikoerper, psme4 antikoerper
    Hintergrund
    Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin- independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Component of the spermatoproteasome, a form of the proteasome specifically found in testis: binds to acetylated histones and promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Also involved in DNA damage response in somatic cells, by promoting degradation of histones following DNA double-strand breaks.
    Molekulargewicht
    211334
    UniProt
    Q14997
    Pathways
    DNA Replication, Synthesis of DNA
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