Nitrotyrosine Antikörper

Produktnummer ABIN7833437

Der Maus Monoklonal anti-Nitrotyrosine Antikörper (Klon EM-30) (ABIN7833437) detektiert spezifisch Nitrotyrosine in WB, IHC (fro) und IHC (p).

Kurzübersicht für Nitrotyrosine Antikörper (ABIN7833437)

Target: Nitrotyrosine

Reaktivität: Bitte anfragen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Nitrotyrosine Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: EM-30

Produktdetails anti-Nitrotyrosine Antikörper

Verwendungszweck: Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30)

Kreuzreaktivität (Details): Nitrotyrosine

Immunogen: NO2-Tyr-CH2-Thyroglobulin

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: (IHC) paraffin: 10 μg/mL, positive tissue: colon cancer epithelium, prostate hyperplasia. (IHC) frozen sections: 10 μg/mL, positive tissue: colon cancer epithelium, prostate hyperplasia. (WB): positive control: NO2-BSA, NO2-HSA.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Immunoglobulin purified on Protein A.

Handhabung: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube,Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Details zu Nitrotyrosine

Target: Nitrotyrosine

Substanzklasse: Chemical

Hintergrund:

Background: Nitrotyrosine can be detected in proteins from a variety of tissues, usually in association with pathological conditions. Reaction of nitric oxide with superoxide produces peroxynitrite, which can undergo heterolytic cleavage into nitronium and hydroxyl ions. Nitration of tyrosine residues by nitronium ion forms nitrotyrosine groups in the respective proteins. Nitrotyrosine is thus a marker for inflammation-associated tissue damage.

Additional information: This antibody detects nitrotyrosine group in biological material, It can be used as a marker for peroxynitrite formation in particular tissues