Rekombinanter ERBB4 Antikörper

Produktnummer ABIN7828663

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch ERBB4 in IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter ERBB4 Antikörper (ABIN7828663)

Target: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ERBB4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: A584

Produktdetails anti-ERBB4 Antikörper

Verwendungszweck: Recombinant HER4/ErbB4 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human HER4/ErbB4 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: IHC 1:200-1:1000,IF 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu ERBB4

Target: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Andere Bezeichnung: HER4/ErbB4

Hintergrund: ALS,HER,ERBB,Proto-oncogene-like protein c-ErbB,Receptor tyrosine-protein kinase erbB,Tyrosine kinase-type cell surface receptor HER,p180erbB,HER4/ErbB,ALS19,HER4,p180erbB4,ERBB4,HER4/ErbB4,Proto-oncogene-like protein c-ErbB-4,Receptor tyrosine-protein kinase erbB-4,Tyrosine kinase-type cell surface receptor HER4,4ICD,Avian erythroblastic leukemia viral oncogene homolog 4,Avian erythroblastic leukemia viral v erb b2 oncogene homolog 4,E4ICD,EC 2.7.10.1,ERBB4 intracellular domain,HER 4,human epidermal growth factor receptor 4,Mer4,MGC138404,Oncogene ERBB4,Receptor protein tyrosine kinase erbB 4 precursor,Receptor tyrosine protein kinase erbB 4,s80HER4,Tyrosine kinase type cell surface receptor HER4,v erb a avian erythroblastic leukemia viral oncogene homolog like 4,v erb a erythroblastic leukemia viral oncogene homolog 4,Verba avian erythroblastic leukemia viral oncogene homolog like 4,Verba erythroblastic leukemia viral oncogene homolog 4,v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian),VERBB2,V-ERB-B2 avian erythroblastic leukemia viral oncogene homolog 4,HER4/ErbB4, like other receptor tyrosine kinase family members, has four ectodomains, a single transmembrane domain and a cytoplasmic tail containing the active tyrosine kinase domain. By binding to neuregulins and/or EGF family ligands, ErbB4 forms either a homodimer or heterodimer with other ErbB family members, which results in receptor activation and signaling. ErbB4 is ubiquitously expressed with the highest expression occurring in brain and heart. The expression of ErbB4 in breast cancer, pediatric brain cancer and other types of carcinomas has been reported in research studies suggesting that ErbB4 expression is involved in both normal tissue development and carcinogenesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: Q15303

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung