ERBB4 Antikörper (AA 1159-1308)
Kurzübersicht für ERBB4 Antikörper (AA 1159-1308) (ABIN7539651)
Target
Alle ERBB4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1159-1308
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Verwendungszweck
- ERBB4 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human ERBB4 (AA: 1159-1308) expressed in E. Coli.
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Isotyp
- IgG1
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anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 29-278) antibody
ERBB4 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1284) antibodyERBB4 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (C-Term) antibodyERBB4 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1159-1308) antibodyERBB4 Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 5G6B4 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1116-1269) antibodyERBB4 Reaktivität: Human IHC Wirt: Maus Monoclonal ERBB4-2581 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1162) antibodyERBB4 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB5687 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1116-1269) antibodyERBB4 Reaktivität: Human, Maus FACS, IF Wirt: Maus Monoclonal HFR-1 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 25-55), (N-Term) antibodyERBB4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB01469 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1188) antibodyERBB4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB6051 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1162) antibodyERBB4 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))
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Andere Bezeichnung
- ERBB4
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Hintergrund
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This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
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Molekulargewicht
- 146.8 kDa
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UniProt
- Q15303
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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