Rekombinanter PTPN12 Antikörper

Produktnummer ABIN7828502

Der Kaninchen Monoklonal anti-PTPN12 Antikörper wird verwendet zum Nachweis von PTPN12 in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für Rekombinanter PTPN12 Antikörper (ABIN7828502)

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PTPN12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A502

Produktdetails anti-PTPN12 Antikörper

Verwendungszweck: Recombinant PTPN12 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human PTPN12 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu PTPN12

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Andere Bezeichnung: PTPN12

Hintergrund: PTPG,PTPN,PTPG1,PTP-PEST,PTPN12,PTP-PEST,Protein tyrosine phosphatase G1,Protein tyrosine phosphatase non receptor type 12,Protein-tyrosine phosphatase G1,PTN12,PTP PEST,Tyrosine protein phosphatase non receptor type 12,Tyrosine-protein phosphatase non-receptor type 12,PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 88 kDa

Observed MW: 120 kDa The actual band is not consistent with the expectation.

UniProt: Q05209