Der Kaninchen Polyklonal anti-PTPN12 Antikörper (ABIN7239389) detektiert spezifisch PTPN12 in WB, ELISA und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
PTPN12
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB54521
unconjugated
Applikationshinweise
WB 1:200-1:1000, IHC 1:100-1:300
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
PTPN12
(Protein Tyrosine Phosphatase G1 (PTPN12))
Andere Bezeichnung
PTPN12
Hintergrund
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis.