Rekombinanter PKC zeta Antikörper

Produktnummer ABIN7828495

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch PKC zeta in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Rekombinanter PKC zeta Antikörper (ABIN7828495)

Target: PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PKC zeta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A658

Produktdetails anti-PKC zeta Antikörper

Verwendungszweck: Recombinant PKC zeta Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human PKC zeta fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu PKC zeta

Target: PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

Andere Bezeichnung: PKC zeta

Hintergrund: PKC,PRKCZ,PKC-ZETA,PKC2,14-3-3-zetaisoform,AI098070,aPKCzeta,C80388,EC 2.7.11.13,included,KPCZ,nPKC zeta,nPKC-zeta,OTTHUMP00000001368,OTTHUMP00000044160,PKC 2,PKC ZETA,Pkcz,PKC-Z,PKCZETA,PKM-zeta,Protein kinase C zeta,Protein kinase C zeta form,Protein kinase C zeta type,Protein Kinase M Zeta,r14-3-3,R74924,zetaPKC,Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 68 kDa

Observed MW: 70 kDa The actual band is not consistent with the expectation.

UniProt: Q05513

Pathways: NF-kappaB Signalweg, RTK Signalweg, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling