Rekombinanter NFKBIB Antikörper

Produktnummer ABIN7828421

Der Kaninchen Monoklonal anti-NFKBIB Antikörper wird verwendet zum Nachweis von NFKBIB in Proben von Human und Maus. Er wurde validiert für WB, IF und FACS.

Kurzübersicht für Rekombinanter NFKBIB Antikörper (ABIN7828421)

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NFKBIB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: A563

Produktdetails anti-NFKBIB Antikörper

Verwendungszweck: Recombinant IKB beta Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human IKB beta fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,FCM 1:50-1:100,IF 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu NFKBIB

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Andere Bezeichnung: IKB beta

Hintergrund: TRIP,NFKBIB,IKBB,TRIP9,I kappa B beta,IkappaBbeta,I-kappa-B-beta,IKB beta,IkB-B,IkBbeta,IkB-beta,NF kappa BIB,NF-kappa-B inhibitor beta,NF-kappa-BIB,Thyroid receptor interacting protein 9,Thyroid receptor-interacting protein 9,TR interacting protein 9,TR-interacting protein 9,TRIP-9,IkB-beta a protein of the NF-kappa-B inhibitor family. IKB beta Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with IKB beta-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 60 kDa

Observed MW: 48 kDa The actual band is not consistent with the expectation.

UniProt: Q15653

Pathways: NF-kappaB Signalweg, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades