Rekombinanter MCM7 Antikörper

Produktnummer ABIN7828393

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch MCM7 in WB, IHC, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human und Green Monkey.

Kurzübersicht für Rekombinanter MCM7 Antikörper (ABIN7828393)

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Green Monkey

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MCM7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: A456

Produktdetails anti-MCM7 Antikörper

Verwendungszweck: Recombinant MCM7 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human MCM7 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:2000-1:10000,IHC 1:50-1:100,IF 1:50,FCM 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu MCM7

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Andere Bezeichnung: MCM7

Hintergrund: CDC,PNAS,P1CDC,PPP1R,P1.1-MCM,MCM,MCM7,CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS146,PPP1R104,formerly,homolog of,regulatory subunit 104,S. cerevisiae,CDABP0042,CDC 47,CDC47 homolog,DNA replication licensing factor MCM7,Homolog of S. cerevisiae Cdc47,MCM 2,MCM 7,MCM7 minichromosome maintenance deficient 7,MCM7_HUMAN,Minichromosome maintainence,Minichromosome Maintainence 7,Minichromosome maintenance complex component 7,Minichromosome maintenance deficient 7,Minichromosome maintenance protein 7,P1.1 MCM3,PNAS 146,Protein phosphatase 1,DNA replication licensing factor MCM7 acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for once per cell cycle DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. MCM7 is also required for S-phase checkpoint activation upon UV-induced damage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 81 kDa

Observed MW: 81 kDa

UniProt: P33993

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA