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MCM7 Antikörper (AA 195-319)

MCM7 Reaktivität: Human IHC, IF, FACS, StM Wirt: Maus Monoclonal MCM7-1467 unconjugated
Produktnummer ABIN6940019
  • Target Alle MCM7 Antikörper anzeigen
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    Bindungsspezifität
    • 27
    • 15
    • 13
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 195-319
    Reaktivität
    • 117
    • 30
    • 23
    • 11
    • 10
    • 9
    • 9
    • 9
    • 4
    • 2
    • 1
    Human
    Wirt
    • 81
    • 35
    • 2
    Maus
    Klonalität
    • 77
    • 41
    Monoklonal
    Konjugat
    • 71
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MCM7 Antikörper ist unkonjugiert
    Applikation
    • 79
    • 34
    • 31
    • 24
    • 21
    • 20
    • 13
    • 13
    • 12
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human MCM7 protein fragment (aa195-319) (exact sequence is proprietary)
    Klon
    MCM7-1467
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product MCM7 Primärantikörper
  • Applikationshinweise

    Positive Control: MCF-7, HEK293, A549, Raji or Ramos cells. Tonsil.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    Andere Bezeichnung
    MCM7 (MCM7 Produkte)
    Synonyme
    CDC47 antikoerper, MCM2 antikoerper, P1.1-MCM3 antikoerper, P1CDC47 antikoerper, P85MCM antikoerper, PNAS146 antikoerper, MCM7 antikoerper, AI747533 antikoerper, Mcmd7 antikoerper, mCDC47 antikoerper, chunp6911 antikoerper, nyz175 antikoerper, sr:nyz175 antikoerper, cdc47 antikoerper, cdc47-2 antikoerper, mcm7 antikoerper, xmcm7 antikoerper, CG4978 antikoerper, DmMCM7 antikoerper, DmeMCM7 antikoerper, Dmel\\CG4978 antikoerper, McM7 antikoerper, Mcp-PCR1 antikoerper, PCR1 antikoerper, anon-EST:Liang-1.66 antikoerper, clone 1.66 antikoerper, minichromosome maintenance complex component 7 antikoerper, mini-chromosome maintenance complex protein 7 antikoerper, minichromosome maintenance complex component 2 antikoerper, minichromosome maintenance complex component 7 L homeolog antikoerper, Minichromosome maintenance 7 antikoerper, minichromosome maintenance complex component 7 S homeolog antikoerper, MCM complex subunit Mcm7 antikoerper, MCM7 antikoerper, CDC47 antikoerper, Mcm7 antikoerper, MCM2 antikoerper, mcm7 antikoerper, mcm7.L antikoerper, mcm7.S antikoerper
    Hintergrund
    The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
    Molekulargewicht
    88kDa
    Gen-ID
    4176
    UniProt
    P33993
    Pathways
    DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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