Rekombinanter HSP27 Antikörper (pSer78)

Produktnummer ABIN7828250

Der Kaninchen Monoklonal anti-HSP27 Antikörper wird verwendet zum Nachweis von HSP27 in Proben von Human. Er wurde validiert für WB, IHC, IF und IP.

Kurzübersicht für Rekombinanter HSP27 Antikörper (pSer78) (ABIN7828250)

Target: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser HSP27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: A811

Produktdetails anti-HSP27 Antikörper

Bindungsspezifität: pSer78

Verwendungszweck: Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: phosphorylated human HSP27 (Ser78) peptide

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:100-1:500,IF 1:50,IP 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu HSP27

Target: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Andere Bezeichnung: HSP27

Hintergrund: SRP,HSPB,HEL-S,HSP,HSPB1,CMT2F,HEL-S-102,HMN2B,HS.76067,HSP27,HSP28,Hsp25,SRP27,28 kDa heat shock protein,DKFZp586P1322,epididymis secretory protein Li 102,Estrogen regulated 24 kDa protein,Estrogen-regulated 24 kDa protein,Heat shock 25 kDa protein 1,Heat shock 27 kDa protein,Heat shock 27kD protein 1,Heat shock 27 kDa protein,Heat shock 27 kDa protein 1,Heat shock 28 kDa protein 1,Heat Shock Protein 27,Heat shock protein beta 1,Heat shock protein beta-1,heat shock protein family B (small) member 1,Hsp 25,HSP 27,Hsp 28,Hsp B1,Stress responsive protein 27,Stress-responsive protein 27,Hsp27 is one of the small HSPs that are constitutively expressed at different levels in various cell types and tissues. Like other small HSPs, HSP27 is regulated at both the transcriptional and posttranslational levels. In response to stress, the HSP27 expression increases several-fold to confer cellular resistance to the adverse environmental change. HSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway. Phosphorylation of HSP27 causes a change in its tertiary structure, which shifts from large homotypic multimers to dimers and monomers. It has been shown that phosphorylation and increased concentration of HSP27 modulates actin polymerization and reorganization. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 23 kDa

Observed MW: 27 kDa The actual band is not consistent with the expectation.

UniProt: P04792

Pathways: MAPK Signalweg, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling