Rekombinanter Gelsolin Antikörper

Produktnummer ABIN7828222

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Gelsolin in WB, FACS und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Gelsolin Antikörper (ABIN7828222)

Target: Gelsolin (GSN)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Gelsolin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: A536

Produktdetails anti-Gelsolin Antikörper

Verwendungszweck: Recombinant Gelsolin Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human Gelsolin fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000,IF 1:50,FCM 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu Gelsolin

Target: Gelsolin (GSN)

Andere Bezeichnung: Gelsolin

Hintergrund: DKFZp313L,GSN,ADF,AGEL,gelsolin,Actin depolymerizing factor,DKFZp313L0718,Brevin,GELS,Actin-depolymerizing factor,Actin-depolymerizing factor,ADF,AGEL,Brevin,GELS,GSN,Gelsolin shares structural and functional homology to villin and adseverin/scinderin. It plays an important role in actin filament assembly by capping and severing actin proteins in a Ca2+-dependent manner. Gelsolin is important for cellular events that require cytoskeletal remodeling. Accordingly, cells from gelsolin knockout mice exhibit motility defects, including a failure to ruffle in response to growth factor stimulation. In humans, defects in gelsolin have been linked to amyloidosis type 5 (AMYL5), a hereditary disease characterized by cranial neuropathy, which appears to result from gelsolin amyloid deposition. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 81 kDa

Observed MW: 81 kDa

UniProt: P06396

Pathways: Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization, Autophagie