Gelsolin Antikörper (AA 543-782)
Kurzübersicht für Gelsolin Antikörper (AA 543-782) (ABIN7267365)
Target
Alle Gelsolin (GSN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 543-782
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Verwendungszweck
- Gelsolin Rabbit pAb
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Sequenz
- PMIIYKGGTS REGGQTAPAS TRLFQVRANS AGATRAVEVL PKAGALNSND AFVLKTPSAA YLWVGTGASE AEKTGAQELL RVLRAQPVQV AEGSEPDGFW EALGGKAAYR TSPRLKDKKM DAHPPRLFAC SNKIGRFVIE EVPGELMQED LATDDVMLLD TWDQVFVWVG KDSQEEEKTE ALTSAKRYIE TDPANRDRRT PITVVKQGFE PPSFVGWFLG WDDDYWSVDP LDRAMAELAA
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 543-782 of human Gelsolin (NP_000168.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Gelsolin (GSN)
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Andere Bezeichnung
- GSN
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Hintergrund
- The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.,GSN;ADF;AGEL;gelsolin,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,Actins,GSN
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Molekulargewicht
- 80kDa/81kDa/85kDa
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Gen-ID
- 2934
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UniProt
- P06396
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Pathways
- Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization, Autophagie
Target
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