Gelsolin Antikörper (N-Term)
Kurzübersicht für Gelsolin Antikörper (N-Term) (ABIN6242369)
Target
Alle Gelsolin (GSN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 230-259, N-Term
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Homologie
- B
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Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This GSN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the N-terminal region of human GSN.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000-1:2000. WB: 1:2000. IHC-P: 1:50~100. FC: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- Gelsolin (GSN)
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Andere Bezeichnung
- GSN
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Hintergrund
- GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this protein are a cause of familial amyloidosis Finnish type (FAF).
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Molekulargewicht
- 85698
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NCBI Accession
- NP_000168, NP_001121134, NP_001121135, NP_001121136, NP_001121137, NP_001121138, NP_001121139, NP_001244958, NP_001244959, NP_937895
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UniProt
- P06396
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Pathways
- Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization, Autophagie
Target
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