Rekombinanter COPS3 Antikörper

Produktnummer ABIN7828134

Der Kaninchen Monoklonal anti-COPS3 Antikörper (Klon A192) (ABIN7828134) detektiert spezifisch COPS3 in WB, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Rekombinanter COPS3 Antikörper (ABIN7828134)

Target: COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser COPS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: A192

Produktdetails anti-COPS3 Antikörper

Verwendungszweck: Recombinant COPS3 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human COPS3 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu COPS3

Target: COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))

Andere Bezeichnung: COPS3

Hintergrund: SGN,Csn,COPS,COPS3,CSN3,SGN3,Constitutive photomorphogenic homolog subunit 3,COP 9 (constitutive photomorphogenic) subunit 3,COP 9 complex homolog subunit 3,COP 9 complex S3,COP 9 complex subunit 3,COP 9 constitutive photomorphogenic homolog subunit 3,COP 9 homolog,COP 9 signalosome complex subunit 3,COP 9 signalosome subunit 3,COP 9 subunit 3,COP9 (constitutive photomorphogenic) subunit 3,COP9 complex homolog subunit 3,COP9 complex S3,COP9 complex subunit 3,COP9 constitutive photomorphogenic homolog subunit 3,COP9 homolog,COP9 signalosome complex subunit 3,COP9 signalosome subunit 3,COP9 subunit 3,COPS 3,CSN 3,JAB 1 containing signalosome subunit 3,JAB1 containing signalosome subunit 3,JAB1-containing signalosome subunit 3,SGN 3,Signalosome subunit 3,Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 44 kDa

Observed MW: 44 kDa

UniProt: Q9UNS2

Pathways: Zellzyklus