Rekombinanter CSF1R Antikörper

Produktnummer ABIN7828128

Der Kaninchen Monoklonal anti-CSF1R Antikörper (Klon A195) (ABIN7828128) detektiert spezifisch CSF1R in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Rekombinanter CSF1R Antikörper (ABIN7828128)

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CSF1R Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: A195

Produktdetails anti-CSF1R Antikörper

Verwendungszweck: Recombinant CSF-1R Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human CSF-1R fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: IHC 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Andere Bezeichnung: CSF-1R

Hintergrund: FIM,CSF1R,C-FMS,CD115,CSF-1R,CSFR,FIM2,FMS,HDLS,M-CSF-R,BANDDOS,CSF-1 receptor,CSF-1-R,Macrophage colony-stimulating factor 1 receptor,MCSF Receptor,Proto-oncogene c-Fms,M-CSFR,c-fms,CSF-1R,FMS,C FMS,CD 115,CD115 antigen,CFMS,Colony stimulating factor 1 receptor,Colony stimulating factor I receptor,CSF 1 R,CSF 1R,CSF1 R,EC 2.7.10.1,FIM 2,FMS proto oncogene,FMS protooncogene,formerly,Macrophage colony stimulating factor 1 receptor,Macrophage colony stimulating factor I receptor,McDonough feline sarcoma viral (v fms) oncogene homolog,M-CSF Receptor,MCSF Receptor,MCSFR,Oncogen FMS,V-FMS McDonough feline sarcoma viral oncogen homolog,Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration, and promotes cancer cell invasion. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P07333

Pathways: RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization