Rekombinanter CDC25C Antikörper
Kurzübersicht für Rekombinanter CDC25C Antikörper (ABIN7828098)
Target
Alle CDC25C Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Recombinant Cdc25C Monoclonal Antibody
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Aufreinigung
- Protein A purified
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Immunogen
- Recombinant human Cdc25C fragment
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Isotyp
- IgG, kappa
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Applikationshinweise
- WB 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Haltbarkeit
- 12 months
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- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
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Andere Bezeichnung
- Cdc25C
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Hintergrund
- CDC,PPP1R,CDC25C,CDC25,PPP1R60,Cdc25C is a protein phosphatase responsible for dephosphorylating and activating cdc2, a crucial step in regulating the entry of all eukaryotic cells into mitosis. Cdc25C is constitutively phosphorylated at Ser216 throughout interphase by c-TAK1, while phosphorylation at this site is DNA damage-dependent at the G2/M checkpoint. When phosphorylated at Ser216, Cdc25C binds to members of the 14-3-3 family of proteins, sequestering Cdc25C in the cytoplasm and thereby preventing premature mitosis. The checkpoint kinases Chk1 and Chk2 phosphorylate Cdc25C at Ser216 in response to DNA damage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Molekulargewicht
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Calculated MW: 53 kDa
Observed MW: 53 kDa
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UniProt
- P30307
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Pathways
- Zellzyklus, M Phase
Target
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