Rekombinanter Caveolin-1 Antikörper (pTyr14)

Produktnummer ABIN7828072

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Caveolin-1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Caveolin-1 Antikörper (pTyr14) (ABIN7828072)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Caveolin-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A813

Produktdetails anti-Caveolin-1 Antikörper

Bindungsspezifität: pTyr14

Verwendungszweck: Recombinant Phospho-Caveolin-1 (Tyr14) Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: phosphorylated human Caveolin-1 (Tyr14) peptide

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Andere Bezeichnung: Caveolin-1

Hintergrund: PPH,CGL,BSCL,MSTP,cell growth-inhibiting protein,OTTHUMP,VIP,BSCL3,CGL3,LCCNS,MSTP085,PPH3,VIP21,CAV1,22 kD,caveolae protein,caveolin 1 alpha isoform,caveolin 1 beta isoform,Caveolin 1 caveolae protein 22 kDa,Caveolin1,Caveolin-1,cell growth-inhibiting protein 32,OTTHUMP00000025031,VIP 21,CAV,Caveolins are the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Three members of the caveolin family (caveolin-1, -2, and -3) have been identified with different tissue distributions. Caveolins form hetero- and homo-oligomers that interact with cholesterol and other lipids. Caveolins are involved in diverse biological functions, including vesicular trafficking, cholesterol homeostasis, cell adhesion, and apoptosis, and are also implicated in neurodegenerative disease. Caveolins interact with multiple signaling molecules, such as Gα subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases, and eNOS. It is believed that caveolins serve as scaffolding proteins for the integration of signal transduction. Phosphorylation at Tyr14 is essential for caveolin association with SH2 or PTB domain-containing adaptor proteins, such as GRB7. Phosphorylation at Ser80 regulates caveolin binding to the ER membrane and entry into the secretory pathway. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 20 kDa

Observed MW: 22 kDa The actual band is not consistent with the expectation.

UniProt: Q03135

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals