Caveolin-1 Antikörper (AA 1-100)

Produktnummer ABIN6137992

Produktdetails anti-Caveolin-1 Antikörper

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caveolin-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MSGGKYVDSE GHLYTVPIRE QGNIYKPNNK AMADELSEKQ VYDAHTKEID LVNRDPKHLN DDVVKIDFED VIAEPEGTHS FDGIWKASFT TFTVTKYWFY

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Caveolin-1 (NP_001744.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Andere Bezeichnung: CAV1 (CAV1 Produkte)

Synonyme: fc07c04 antikoerper, wu:fc07c04 antikoerper, Cav-1 antikoerper, bscl3 antikoerper, cav1 antikoerper, cav1a antikoerper, cgl3 antikoerper, vip21 antikoerper, cav1b antikoerper, caveolin-1 antikoerper, cav antikoerper, mstp085 antikoerper, Caveolin-1 antikoerper, CAV1 antikoerper, cav-1 antikoerper, Cav antikoerper, caveolin 1 antikoerper, BSCL3 antikoerper, CGL3 antikoerper, MSTP085 antikoerper, PPH3 antikoerper, VIP21 antikoerper, caveolin 1 antikoerper, caveolin 1 L homeolog antikoerper, caveolin 1 S homeolog antikoerper, caveolin 1, caveolae protein antikoerper, caveolin 1, caveolae protein, 22kDa antikoerper, Caveolin antikoerper, cav1 antikoerper, cav1.L antikoerper, cav1.S antikoerper, CAV1 antikoerper, Cav1 antikoerper, cav-1 antikoerper

Hintergrund: The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.,BSCL3,CGL3,LCCNS,MSTP085,PPH3,VIP21,CAV1,Cancer,Tumor biomarkers,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Insulin Receptor Signaling Pathway,Cardiovascular,Hypoxia,Lipids,CAV1

Molekulargewicht: 17 kDa/20 kDa

Gen-ID: 857

UniProt: Q03135

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals