Rekombinanter CD79a Antikörper
Kurzübersicht für Rekombinanter CD79a Antikörper (ABIN7828036)
Target
Alle CD79a (CD79A) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- Recombinant CD79a Monoclonal Antibody
-
Aufreinigung
- Protein A purified
-
Immunogen
- Recombinant human CD79a fragment
-
Isotyp
- IgG, kappa
-
-
-
-
Applikationshinweise
- WB 1:1000-1:5000,IHC 1:200-1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
-
Andere Bezeichnung
- CD79a
-
Hintergrund
- CD79A;IGA;MB-1;CD79a molecule;CD79A antigen;MB1;MB1;Ig&alpha,Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
Molekulargewicht
-
Calculated MW: 25 kDa
Observed MW: 44-48 kDa The actual band is not consistent with the expectation.
-
UniProt
- P11912
-
Pathways
- BCR Signaling
Target
-