Rekombinanter TIGIT Antikörper

Produktnummer ABIN7826146

Dieser Kaninchen Monoklonal Antikörper erkennt spezifisch TIGIT in IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter TIGIT Antikörper (ABIN7826146)

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TIGIT Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: HMV323

Produktdetails anti-TIGIT Antikörper

Verwendungszweck: TIGIT antibody (HMV323)

Immunogen: Recombinant human TIGIT fragment

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:200

Kommentare:

Positive Control: Tonsil: A moderate to strong TIGIT staining should be seen in a subset of germinal centre cells (CD4+ follicular T helper cells located in the germinal centre periphery orientated towards the tonsil surface epithelium). Subsets of other lymphocytes should also be positive but less intense.

Product Description/Background: TIGIT antibody validated for immunohistochemistry on 76 different Normal Tissues

Negative Control: Tonsil: TIGIT staining should be absent in all epithelial cells and in most lymphocytes.

Protokoll: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37 °C for 60 minutes.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non- hazardous. No MSD required.

Haltbarkeit: 24 months

Details zu TIGIT

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Andere Bezeichnung: TIGIT

Hintergrund: Gene Alias: T cell immunoreceptor with Ig and ITIM domains , VSIG9 , VSTM3 , WUCAM

UniProt: Q495A1

Pathways: Cancer Immune Checkpoints