CSF1R Antikörper (AA 409-977)

Produktnummer ABIN7825319

Der Kaninchen Polyklonal anti-CSF1R Antikörper (ABIN7825319) detektiert spezifisch CSF1R in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Zebrafisch (Danio rerio).

Kurzübersicht für CSF1R Antikörper (AA 409-977) (ABIN7825319)

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSF1R Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-CSF1R Antikörper

Bindungsspezifität: AA 409-977

Verwendungszweck: Anti-Zebrafish M-CSFR/CSF1R Antibody

Produktmerkmale: Anti-Zebrafish M-CSFR/CSF1R Antibody N6. Tested in IHC applications. This antibody reacts with Zebrafish.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived zebrafish M-CSFR/CSF1R recombinant protein (Position: D409-C977)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry, 2-5 μg/mL, Zebrafish

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Andere Bezeichnung: CSF1R

Hintergrund: CSF1R(Colony-Stimulating Factor 1 Receptor) also known as MCSFR, FMS, c-FMS, CD115, ONCOGENE FMS or CD115 ANTIGEN, encodes a tyrosine kinase growth factor receptor for colony-stimulating factor-1, the macrophage-and monocyte-specific growth factor. The gene is located on long arm of chromosome 5(5q32) on the Crick(minus) strand. The as-yet-unidentified°CSF1 Rpromoter/enhancer sequences may be confined to the nucleotides separating the 2 genes or could potentially lie within the PDGFR gene itself. The encoded protein is a single pass type I membrane protein and acts as the receptor for°Colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. The encoded protein is atyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Kondo et al.(2000) showed that the endogenous myelomonocytic cytokine receptors for GM-CSF and macrophage colony-stimulating factor(CSF1R) are expressed at low to moderate levels on the more primitive hematopoietic stem cells, are absent on common lymphoid progenitors, and are upregulated after myeloid lineage induction by IL2.

UniProt: Q9I8N6

Pathways: RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization