ATG5 Antikörper (AA 118-155)

Produktnummer ABIN7825269

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ATG5 in IHC. Es zeigt Reaktivität gegenüber Proben von Zebrafisch (Danio rerio).

Kurzübersicht für ATG5 Antikörper (AA 118-155) (ABIN7825269)

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-ATG5 Antikörper

Bindungsspezifität: AA 118-155

Verwendungszweck: Anti-Zebrafish ATG5 Antibody

Produktmerkmale: Anti-Zebrafish ATG5 Antibody (ABIN7825269). Tested in IHC applications. This antibody reacts with Zebrafish.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived zebrafish ATG5 recombinant protein (Position: S118-L155).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry, 2-5 μg/mL, Zebrafish

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu ATG5

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Andere Bezeichnung: ATG5

Hintergrund: Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is also known as APG5 or ASP, and this gene is mapped to 6q21. It is found that knockdown of ATG5 in hepatocytes increased triglyceride levels with oleate or a second endogenous stimulus for triglyceride formation. These hepatocytes with ATG5 knockdown also had increased lipid droplet number and size. ATG5 is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.

Gen-ID: 494180

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagie