SPTAN1 Antikörper (AA 30-110)

Produktnummer ABIN739415

Der Kaninchen Polyklonal anti-SPTAN1 Antikörper wird verwendet zum Nachweis von SPTAN1 in Proben von Human. Er wurde validiert für IHC (p), IF (cc), IF (p) und IHC (fro).

Kurzübersicht für SPTAN1 Antikörper (AA 30-110) (ABIN739415)

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPTAN1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-SPTAN1 Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: Spectrin alpha chain, non-erythrocytic 1 Antibody

Homologie: Human,Mouse,Rat,Dog,Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Spectrin alpha chain, non-erythrocytic 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SPTAN1

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Andere Bezeichnung: Spectrin alpha Chain, Non-Erythrocytic 1

Hintergrund:

Synonyms: SPTN1_HUMAN, Alpha Fodrin, Spectrin-Alpha, SPEC, Spectrin, alpha, non-erythrocy tic 1 variant, Spectrin alpha chain, non-erythrocytic 1, Alpha-II spectrin, Fodrin alpha chain, Spectrin, non-erythroid alpha subunit, SPTAN1, SPTA2, alpha-II spectrin, spectrin, non-erythroid alpha chain, alpha-fodrin, spectrin, non-erythroid alpha subunit, spectrin alpha chain, non-erythrocytic 1, EIEE5, NEAS.

Background: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].

Gen-ID: 6709

Pathways: Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization