C3 Antikörper (Biotin)

Produktnummer ABIN739335

Produktdetails anti-C3 Antikörper (Biotin)

Target: C3 (Complement Component 3 (C3))

Reaktivität: Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser C3 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: human Complement C3 purified from human plasma

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu C3

Target: C3 (Complement Component 3 (C3))

Andere Bezeichnung: Complement C3 (C3 Produkte)

Hintergrund:

Synonyms: Acylation stimulating protein cleavage product, Acylation-stimulating protein cleavage product, AHUS5, ARMD9, ASP, ASP, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody C3 antibody C3a anaphylatoxin, CO3_HUMAN, Complement C3 alpha chain, Complement C3, Complement C3 beta chain, Complement C3 precursor, Complement C3b alpha chain, Complement C3c alpha' chain fragment 2, Complement C3c fragment, Complement C3d fragment, Complement C3f fragment, Complement C3g fragment, Complement component 3, Complement component 3 precursor, Complement component C3, Complement factor 3, CPAMD1, Plp.

Background: The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.

Gen-ID: 718

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling