Rekombinanter ATM Antikörper (AA 2550-2600)
Kurzübersicht für Rekombinanter ATM Antikörper (AA 2550-2600) (ABIN7795796)
Target
Alle ATM Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 2550-2600
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Verwendungszweck
- Rabbit anti-ATM Recombinant Monoclonal Antibody [BLR359N]
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Aufreinigung
- Purified
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Immunogen
- between 2550 and 2600
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Isotyp
- IgG
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anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody
ATM Reaktivität: Human WB, IHC, ELISA, IF, IP, FACS, FM Wirt: Maus Monoclonal 10H11-E12 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibodyATM Reaktivität: Human WB, IHC, ELISA, IF, IP, FACS, FM Wirt: Maus Monoclonal 10H11-E12 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (C-Term) antibodyATM Reaktivität: Human, Maus WB, IHC, ELISA, IF, IP, ICC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2484-2748) antibodyATM Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2681-2750) antibodyATM Reaktivität: Human, Maus WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) antibodyATM Reaktivität: Human WB, IHC, ELISA, IP Wirt: Kaninchen Monoclonal 4E11 unconjugated Recombinant Antibody
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody (HRP)ATM Reaktivität: Human WB, IHC, ELISA, FM Wirt: Maus Monoclonal 10H11-E12 HRP
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibodyATM Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 7C10D8 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 486-742) antibodyATM Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) antibodyATM Reaktivität: Human IHC, ELISA, FACS Wirt: Kaninchen Monoclonal 3G11 unconjugated Recombinant Antibody
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Applikationshinweise
- ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,WB,11,000,IP,6 μL/mg lysate
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1000 μg/mL
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Buffer
- Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- ATM (Ataxia Telangiectasia Mutated (ATM))
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Andere Bezeichnung
- ATM
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Hintergrund
- Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4.
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Gen-ID
- 472
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UniProt
- Q13315
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Pathways
- p53 Signalweg, Apoptose, DNA Reparatur, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
Target
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