Rekombinanter IL-5 Antikörper (AA 20-134)
Kurzübersicht für Rekombinanter IL-5 Antikörper (AA 20-134) (ABIN7795773)
Target
Alle IL-5 (IL5) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 20-134
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Verwendungszweck
- Rabbit anti-IL-5 Recombinant Monoclonal Antibody [BLR343M]
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Aufreinigung
- Purified
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Immunogen
- residues 20-134
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Isotyp
- IgG
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Applikationshinweise
- WB,11000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1000 μg/mL
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Buffer
- Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- IL-5 (IL5) (Interleukin 5 (IL5))
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Andere Bezeichnung
- IL-5
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Hintergrund
- IL-5 is a homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. IL-5 also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. IL-5 exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P05113].
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Gen-ID
- 3567
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UniProt
- P05113
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Pathways
- JAK-STAT Signalweg, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
Target
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