Rekombinanter BRCA1 Antikörper (AA 525-575)
Kurzübersicht für Rekombinanter BRCA1 Antikörper (AA 525-575) (ABIN7795735)
Target
Alle BRCA1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 525-575
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Verwendungszweck
- Rabbit anti-BRCA1 Recombinant Monoclonal Antibody [BLR319M]
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Aufreinigung
- Purified
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Immunogen
- Between 525 and 575
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Isotyp
- IgG
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anti-Breast Cancer 1 (BRCA1) (AA 120-220) antibody
BRCA1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 19-83) antibodyBRCA1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 229-335) antibodyBRCA1 Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 6C6D2 unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 1661-1863) antibodyBRCA1 Reaktivität: Human, Ratte, Maus WB, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 445-620) antibodyBRCA1 Reaktivität: Human IHC Wirt: Maus Monoclonal BRCA1-1398 unconjugated
anti-Breast Cancer 1 (BRCA1) (Ser184), (Ser186) antibodyBRCA1 Reaktivität: Human, Ratte WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 1681-1781) antibodyBRCA1 Reaktivität: Human, Ratte, Maus WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 1314-1600), (AA 1314-1864) antibodyBRCA1 Reaktivität: Human WB, IF, IP, ICC, FACS Wirt: Maus Monoclonal RAY unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 1524-1781) antibodyBRCA1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (pSer1524) antibodyBRCA1 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IP,6 μL/mg lysate,WB,11000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1000 μg/mL
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Buffer
- Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- BRCA1 (Breast Cancer 1 (BRCA1))
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Andere Bezeichnung
- BRCA1
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Hintergrund
- BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination.
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Gen-ID
- 12189
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UniProt
- P48754
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Pathways
- Zellzyklus, DNA Reparatur, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
Target
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