Rekombinanter IL-10 Antikörper

Produktnummer ABIN7795732

Dieser Anti-IL-10 Antikörper ist ein Kaninchen Monoklonal Antikörper zur Detektion von IL-10 in WB, IHC und IP. Geeignet für Human.

Kurzübersicht für Rekombinanter IL-10 Antikörper (ABIN7795732)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser IL-10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: BLR317M

Produktdetails anti-IL-10 Antikörper

Verwendungszweck: Rabbit anti-IL-10 Recombinant Monoclonal Antibody [BLR317M]

Aufreinigung: Purified

Immunogen: Residues 19-178

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,6 μL/mg lysate,WB,11,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Andere Bezeichnung: IL-10

Hintergrund: IL-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. IL-10 has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. [taken from NCBI Entrez Gene (Gene ID: 3586)].

Gen-ID: 3586

UniProt: P22301

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints