IGF1R Antikörper
Kurzübersicht für IGF1R Antikörper (ABIN7795596)
Target
Alle IGF1R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Mouse anti-IGF1R Monoclonal Antibody [BC10]
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Aufreinigung
- Purified
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Immunogen
- IGF1R
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Isotyp
- IgG2a
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Applikationshinweise
- ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 500 μg/mL
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Buffer
- Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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Andere Bezeichnung
- IGF1R
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Hintergrund
- IGF1R is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1) and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. IGF1R is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [taken from NCBI Entrez Gene (Gene ID: 3480)].
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Gen-ID
- 3480
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UniProt
- P08069
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Pathways
- RTK Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagie
Target
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