Rekombinanter TIGIT Antikörper
Kurzübersicht für Rekombinanter TIGIT Antikörper (ABIN7795514)
Target
Alle TIGIT Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Expressionssystem
- Mammalian cells
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Verwendungszweck
- Recombinant Anti-mouse TIGIT Monoclonal Antibody (Clone: 10A7), Human IgG1 Fc Silent Kappa
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Produktmerkmale
- The 10A7 antibody binds to the TIGIT protein (WUCAM, Vstm3 or VSIG9), a novel immune checkpoint receptor with inhibitory function. TIGIT is expressed on T cells and natural killer (NK) cells, and several human cancers, including melanoma, NSCLC, and colorectal cancer. Similar to PD-1, the TIGIT receptor limits antitumor immune response in cancer.
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Aufreinigung
- Protein A or G affinity column
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Reinheit
- >95 % by reducing SDS-PAGE
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Isotyp
- Fc Silenced, IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- > 3 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
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Andere Bezeichnung
- TIGIT
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Pathways
- Cancer Immune Checkpoints
Target
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