Rekombinanter PD-1 Antikörper

Produktnummer ABIN7795507

Der Ratte Monoklonal anti-PD-1 Antikörper (Klon 29F-1A12) (ABIN7795507) detektiert spezifisch PD-1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Rekombinanter PD-1 Antikörper (ABIN7795507)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser PD-1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 29F-1A12

Produktdetails anti-PD-1 Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: Recombinant Anti-mouse PD1 Monoclonal Antibody (Clone: 29F.1A12.1), Rat IgG2a Kappa

Produktmerkmale: The rat anti-mouse PD-1 monoclonal antibody 29F.1A12 (rat IgG2a kappa) reacts with the mouse PD-1 protein (programmed death-1 or CD279) encoded by the mouse Pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD-1 and anti-mouse PD-L1 antibodies which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The 29F.1A12 monoclonal antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein. Our recombinant 29F.1A12 antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse PD-1 monoclonal antibody (hybridoma clone name or number: 29F.1A12).

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: PD1

Pathways: Cancer Immune Checkpoints