RAD52 Antikörper (AA 101-200)

Produktnummer ABIN735758

Der Kaninchen Polyklonal anti-RAD52 Antikörper wird verwendet zum Nachweis von RAD52 in Proben von Human. Er wurde validiert für IHC (p), IF (p), IF (cc) und IHC (fro).

Kurzübersicht für RAD52 Antikörper (AA 101-200) (ABIN735758)

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD52 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-RAD52 Antikörper

Bindungsspezifität: AA 101-200

Verwendungszweck: Rad52 Polyclonal Antibody

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Rad52

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RAD52

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Andere Bezeichnung: Rad52

Hintergrund:

Synonyms: DNA repair protein RAD52, DNA repair protein RAD52 homolog, RAD 52, RAD52 homolog S. cerevisiae, RAD52 homolog, Recombination protein RAD52, Rhabdomyosarcoma antigen MU RMS 40.23.

Background: DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which include RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.

Gen-ID: 5893

Pathways: DNA Reparatur