RAD52 Antikörper (pTyr104)

Produktnummer ABIN7223910

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RAD52 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Affe.

Kurzübersicht für RAD52 Antikörper (pTyr104) (ABIN7223910)

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Reaktivität: Human, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD52 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RAD52 Antikörper

Bindungsspezifität: pTyr104

Verwendungszweck: Rabbit Anti-Rad52 (phospho Tyr104) Polyclonal Antibody

Spezifität: Phospho-Rad52 (Y104) Polyclonal Antibody detects endogenous levels of Rad52 protein only when phosphorylated at Y104.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Rad52 Phospho-Tyr104

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RAD52

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Andere Bezeichnung: Rad52

Hintergrund: RAD52, DNA repair protein RAD52 homologThe protein encoded by RAD52 (RAD52 homolog, DNA repair protein) shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of RAD52 is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of RAD52 have been described, but their full-length nature is not known.

Molekulargewicht: 46kD

Gen-ID: 5893

UniProt: P43351

Pathways: DNA Reparatur