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VEGFR2/CD309 Antikörper (pTyr1175)

Dieses Anti-VEGFR2/CD309-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von VEGFR2/CD309 in WB, IHC und ELISA. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7674409

Kurzübersicht für VEGFR2/CD309 Antikörper (pTyr1175) (ABIN7674409)

Target

Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigen
VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reaktivität

  • 317
  • 207
  • 139
  • 17
  • 10
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 286
  • 65
  • 37
  • 3
  • 1
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 277
  • 118
Polyklonal

Konjugat

  • 174
  • 34
  • 19
  • 13
  • 11
  • 9
  • 9
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser VEGFR2/CD309 Antikörper ist unkonjugiert

Applikation

  • 216
  • 117
  • 113
  • 112
  • 64
  • 28
  • 26
  • 26
  • 24
  • 15
  • 13
  • 13
  • 9
  • 7
  • 7
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Bindungsspezifität

    • 37
    • 34
    • 27
    • 23
    • 20
    • 16
    • 16
    • 11
    • 11
    • 10
    • 9
    • 9
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1175

    Verwendungszweck

    Phospho-VEGF Receptor 2 antibody

    Aufreinigung

    Immunogen affinity purified

    Reinheit

    ≥95 % as determined by SDS-PAGE

    Immunogen

    A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500 - 1:1000, IHC: 1:50 - 1:100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze / thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Haltbarkeit

    12 months
  • Target

    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

    Andere Bezeichnung

    VEGF Receptor 2

    Hintergrund

    Synonyms: Vascular endothelial growth factor receptor 2 (VEGFR-2)|Fetal liver kinase 1 (FLK-1)|Kinase insert domain receptor (KDR)|Protein-tyrosine kinase receptor flk-1|KDR|FLK1|VEGFR2

    Background: KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.

    Molekulargewicht

    250 kDa

    Gen-ID

    3791

    UniProt

    P35968

    Pathways

    RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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