PFKFB3 Antikörper
Kurzübersicht für PFKFB3 Antikörper (ABIN7674357)
Target
Alle PFKFB3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- PFKFB3-Specific antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
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Isotyp
- IgG
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anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 400-500) antibody
PFKFB3 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 412-520) antibodyPFKFB3 Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 3F3 unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 454-484), (C-Term) antibodyPFKFB3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB04030 unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 1-520) antibodyPFKFB3 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 454-484) antibodyPFKFB3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (C-Term) antibodyPFKFB3 Reaktivität: Human WB, IP, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 401-520) antibodyPFKFB3 Reaktivität: Human, Ratte, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (pSer467) antibodyPFKFB3 Reaktivität: Human, Ratte, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (AA 1-520) antibodyPFKFB3 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) (C-Term) antibodyPFKFB3 Reaktivität: Human, Ratte, Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
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Andere Bezeichnung
- PFKFB3
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Hintergrund
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Synonyms: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3, PFK/FBPase 3)|6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme|Renal carcinoma antigen NY-REN-56|iPFK-2|PFKFB3
Background: PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5. This antibody is specific to PFKFB3.
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Molekulargewicht
- 58 kDa
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Gen-ID
- 5209
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UniProt
- Q16875
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Pathways
- AMPK Signaling, Regulation of Carbohydrate Metabolic Process
Target
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