CD44 Antikörper (PE-Cy5)

Produktnummer ABIN7673857

Dieses Anti-CD44-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von CD44 in FACS. Geeignet für Human und Maus.

Kurzübersicht für CD44 Antikörper (PE-Cy5) (ABIN7673857)

Target: CD44

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD44 Antikörper ist konjugiert mit PE-Cy5

Applikation: Flow Cytometry (FACS)

Klon: IM7

Produktdetails anti-CD44 Antikörper (PE-Cy5)

Verwendungszweck: PE-Cy5 Anti-Human/Mouse CD44 Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44

Hintergrund:

Synonyms: MDU2MDU3MIC4|CD44|CD44 antigen|CDw44|Epican|LHR|PGP-1|PGP-I|Phagocytic glycoprotein 1|Phagocytic glycoprotein I

Background: CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Molekulargewicht: 0

Gen-ID: 12505960

UniProt: P15379, P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling