IRAK3 Antikörper (AA 428-596)
Kurzübersicht für IRAK3 Antikörper (AA 428-596) (ABIN7673412)
Target
Alle IRAK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 428-596
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Verwendungszweck
- IRAK3 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 428-596aa
Immunogen: IRAK3
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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Andere Bezeichnung
- IRAK3
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Hintergrund
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Synonyms: Interleukin-1 receptor-associated kinase 3 (IRAK-3)|IL-1 receptor-associated kinase M (IRAK-M)|Inactive IL-1 receptor-associated kinase 3|IRAK3
Background: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
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Molekulargewicht
- 68 kDa
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Gen-ID
- 11213
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UniProt
- Q9Y616
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
Target
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