Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C Valid for 1 month or -20°C Valid for 12 months
Haltbarkeit
12 months
Target
C3
(Complement Component 3 (C3))
Andere Bezeichnung
Complement C3
Hintergrund
ASP,CPAMD1,AHUS5,ARMD9,C3a,C3b,The complement system is an important effector which bridges the innate and adaptive immune systems . The third component of complement, C3, plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. Human C3, composed of α and β chains (115 and 75 kDa, respectively). Activation of C3 convertase cleaves the C3 α-subunit to generate C3a, which acts as an anaphylatoxin to mediate the local inflammatory response. C3b is further cleaved into iC3b, C3c, C3dg, and C3f.