HLA DQ Antikörper (PE,Cy5)

Produktnummer ABIN7670250

Dieser Maus Monoklonal Antikörper erkennt spezifisch HLA DQ in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für HLA DQ Antikörper (PE,Cy5) (ABIN7670250)

Target: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HLA DQ Antikörper ist konjugiert mit PE,Cy5

Applikation: Flow Cytometry (FACS)

Klon: 1a3

Produktdetails anti-HLA DQ Antikörper (PE,Cy5)

Verwendungszweck: PE/Cyanine5 Anti-Human HLA-DQ Antibody[1a3]

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Handhabung: Please protected from prolonged exposure to light and do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months.

Haltbarkeit: 12 months

Details zu HLA DQ

Target: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Andere Bezeichnung: HLA-DQ

Hintergrund: Muc-18,MCAM,Mel-CAM,S-endo,HLA-DQ is also known as MHC class II DQ monomorphic antigen. The major histocompatibility complex is composed of two heterodimeric glycoproteins (α and β chains) with apparent molecular weights of 27 and 32 kD. In contrast to other MHC class II molecules, both polypeptide chains of HLA-DQ are polymorphic, with the α chain showing an extremely high degree of polymorphism. HLA-DQ is expressed on B cells in the peripheral blood, and weakly expressed on activated T cells and some monocytes. HLA-DQ is absent on hematopoietic progenitors, resting T cells, erythrocytes, and platelets. HLA-DQ is expressed after HLA-DR and HLA-DP in hematopoietic development. HLA-DQ presents peptide fragments mainly from degraded intravesicular and extracellular proteins to CD4+ T lymphocytes. Specific alleles of HLA-DQ have been linked to the pathogenesis of several autoimmune diseases (including diabetes), both as a susceptibility and resistance factor depending on the particular polymorphism.

UniProt: P43121