ITGAL
Reaktivität: Human
FACS, IP
Wirt: Maus
Monoclonal
MEM-25
Biotin
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
5 μL/tests
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
Handhabung
Please protected from prolonged exposure to light and do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
This product can be stored at 2-8°C for 12 months.
Haltbarkeit
12 months
Target
ITGAL
(Integrin alpha-L (ITGAL))
Andere Bezeichnung
CD11a
Hintergrund
CD180,Radio-protective 105-kD protein,RP105,CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).