Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
≥ 1 mg/mL
Buffer
PBS, pH 7.2. Contains 0.05 % proclin 300.
Konservierungsmittel
ProClin
Vorsichtsmaßnahmen
This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
avoid freeze / thaw cycles.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Haltbarkeit
12 months
Target
KLRC1
(Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
Andere Bezeichnung
CD159a
Hintergrund
Klrc1,NKG2A,CD159a, also known as NKG2A or KLRC1 (killer cell lectin-like receptor subfamily C, member 1), is a 43 kD type II transmembrane protein with extracellular C-type lectin domains. It belongs to the killer cell lectin-like receptor family also known as the NKG2 family. It is expressed on NK and NKT cells and activated CD8+ T cells. NKG2A binds to non-classical MHC class I molecule Qa-1 and causes inhibition of NK cell-mediated target-cell lysis.